Binding Strength

In DrugBank, the binding strength of a drug to a target, enzyme, carrier, or transporter (or vice versa) refers to the relative affinity at which these two aforementioned groups attach or associate with each other.  The specific numerical pharmacokinetic demarcation between binding strength values varies depending on the resource or study cited. Nevertheless, the binding strengths of certain drugs versus that of others is also often described in relation to each other so that it is possible to consider certain drugs as having weak, moderate, or strong binding strengths to a target, enzyme, carrier, or transporter when compared to other drugs. In that sense, curated data in DrugBank will frequently refer to certain enzymes, etc. as weak, moderate, or strong inhibitors, inducers, and so on.