Evidence level
Synonyms:
- Evidence level 1
- Evidence level 2
- level of evidence
In DrugBank, a drug interaction is given a level of evidence, denoted by "Evidence level 1" or "Evidence level 2". These terms refer to the type of information that was used to generate this drug interaction in our database. The evidence levels are defined, according to DrugBank, as follows:
Evidence level 1
This drug interaction is based on information formally provided in official prescribing information such as US Food and Drug Administration (FDA) labels, European Medicines Agency (EMA) records, Health Canada (DPD) labels, or National Institutes of Health (NIH) labels.
Evidence level 1
This drug interaction is based on information formally provided in official prescribing information such as US Food and Drug Administration (FDA) labels, European Medicines Agency (EMA) records, Health Canada (DPD) labels, or National Institutes of Health (NIH) labels.
Evidence level 2
This drug interaction is based on scientific and clinical knowledge referenced from a variety of evidence sources that include, but are not limited to, systematic reviews, randomized controlled trials, case reports, in vitro studies, retrospective and cohort studies, as well as established pharmacokinetic and pharmacodynamic properties of the drugs involved.
